Previous research has shown that students employ intuitive thinking when understanding scientific concepts. Three types of intuitive thinking-essentialist, teleological, and anthropic thinking-are used in biology learning and can lead to misconceptions. However, it is unknown how commonly these types of intuitive thinking, or cognitive construals, are used spontaneously in students' explanations across biological concepts and whether this usage is related to endorsement of construal-consistent misconceptions. In this study, we examined how frequently undergraduate students across two U.S. universities (N = 807) used construal-consistent language (CCL) to explain in response to open-ended questions related to five core biology concepts (e.g., evolution), how CCL use differed by concept, and how this usage was related to misconceptions agreement. We found that the majority of students used some kind of CCL in the responses to these open-ended questions and that CCL use varied by target concept. We also found that students who used CCL in their response agreed more strongly with misconception statements, a relationship driven by anthropocentric language use, or language that focused on humans. These findings suggest that American university students use intuitive thinking when reasoning about biological concepts with implications for their understanding.