Multimodal transesophageal echocardiography in the surgical resection of patients with hepatocellular carcinoma and inferior vena cava tumor thrombus

Background: The incidence and mortality rate of hepatocellular carcinoma (HCC) are increasing globally. HCC with inferior vena cava tumor thrombus (HCCIVCTT) represents an advanced stage of the disease. Research suggests that for patients with advanced HCCIVCTT, liver resection combined with thrombectomy is a safe and feasible option that can provide moderate survival benefit. The aim of this study was to evaluate the application value of multimodal transesophageal echocardiography (TEE) in the perioperative period for patients with HCCIVCTT.

Methods: TEE was used for routine intraoperative examination in 17 patients to determine the location and classification of tumor thrombi, guide the proper placement of the inferior vena cava occlusion band during surgery, and evaluate whether the tumor thrombus was completely removed postoperatively.

Results: Among the 17 patients with HCCIVCTT, tumor thrombi invaded the hepatic veins and extended into the inferior vena cava, with 3 cases of extension into the right atrium. The tumor thrombi varied in shape, size, and echogenicity, with high-velocity turbulent flow signals observed within the occluded vessels. There were 10 cases of type I, 4 cases of type II, and 3 cases of type III. Under the guidance of intraoperative TEE, preocclusion bands were successfully placed above the tumor thrombi in type I and II patients, with real-time dynamic monitoring showing no rupture or dislodgement of the thrombi, and postoperatively, the thrombi appeared to be completely removed.

Conclusions: TEE plays an important role in the perioperative management of HCCIVCTT. It can aid in deterring the type of tumor thrombus, selecting the suitable surgical method, and postoperatively assessing the completeness of tumor thrombus removal.