Correlation between peripheral blood inflammatory markers and delayed cerebral ischemia after intracerebral hemorrhage

Objective: To assess the predictive value of peripheral blood inflammatory markers for delayed cerebral ischemia (DCI) in patients with intracerebral hemorrhage (ICH) and explore methods for early intervention.

Methods: This single-center retrospective study reviewed medical records of ICH patients admitted to Cangzhou People's Hospital over a 12-month period from January 2022 to December 2023. Of the 150 identified patients with ICH, including 80 patients without DCI (control group) and 70 with DCI (observation group). Demographics and blood biochemical markers during hospitalization were recorded. Binary logistic regression was used to identify independent factors influencing DCI occurrence.

Results: Significant differences were observed between the two groups in neutrophil percentage, lymphocyte percentage, lymphocytes absolute and neutrophil-to-lymphocyte ratio (NLR) (all P<0.05). Logistic regression analysis identified mRS score, lymphocyte percentage, educational level, uric acid, neutrophils percentage, and NLR as independent risk factors for DCI.

Conclusion: Neutrophil percentage and NLR are independent factors influencing delayed cerebral ischemia after intracerebral hemorrhage. These markers are readily accessible and may provide valuable insights for early ICH management.