Compressed SENSE acceleration factor influence on magnetic resonance image quality in patients with endometrial cancer

Olivera Nikolić; Marijana Basta Nikolić; Miloš Pantelić; Sonja Lukač; Viktor Till; Sanja Stojanović; Una Molnar

doi:10.1016/j.ejmp.2025.104899

Compressed SENSE acceleration factor influence on magnetic resonance image quality in patients with endometrial cancer

Phys Med. 2025 Jan 16:130:104899. doi: 10.1016/j.ejmp.2025.104899. Online ahead of print.

Authors

Olivera Nikolić¹, Marijana Basta Nikolić², Miloš Pantelić³, Sonja Lukač⁴, Viktor Till⁵, Sanja Stojanović⁶, Una Molnar⁷

Affiliations

¹ Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia; Center for Radiology, University Clinical Center of Vojvodina, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia. Electronic address: [email protected].
² Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia; Center for Radiology, University Clinical Center of Vojvodina, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia. Electronic address: [email protected].
³ Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia; Clinic for Gynecology and Obstetrics, University Clinical Center of Vojvodina, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia. Electronic address: [email protected].
⁴ Center for Radiology, University Clinical Center of Vojvodina, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia. Electronic address: [email protected].
⁵ Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia; Center for Radiology, University Clinical Center of Vojvodina, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia. Electronic address: [email protected].
⁶ Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia; Center for Radiology, University Clinical Center of Vojvodina, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia. Electronic address: [email protected].
⁷ Center for Radiology, University Clinical Center of Vojvodina, Hajduk Veljkova 1-9, 21000 Novi Sad, Serbia; Faculty of Sciences, University of Novi Sad, Trg Dositeja Obradovića 3, 21000 Novi Sad, Serbia. Electronic address: [email protected].

PMID: 39823914
DOI: 10.1016/j.ejmp.2025.104899

Abstract

Objectives: To investigate the impact of compressed sensing - sensitivity encoding (CS-SENSE) acceleration factor on the diagnostic performance of magnetic resonance imaging (MRI) within standard female pelvis protocol in patients with endometrial cancer.

Methods: T2-weighted turbo spin echo (TSE) sequence from standard female pelvic MRI protocol was chosen due to its long acquisition time and essential role in the evaluation of morphological characteristics of the female pelvic anatomical structures. Fully sampled reference scans and multiple prospectively 2x to 5x under-sampled CS-SENSE scans were acquired. Retrospectively, under-sampled scans were compared to fully sampled scans and visually assessed for image quality and diagnostic quality by two independent radiologists dedicated to urogenital imaging with different experience levels.

Results: Images obtained with CS-SENSE accelerated acquisition were of diagnostically acceptable quality at up to 3x acceleration for T2 TSE in both axial and sagittal planes (with an acquisition time reduction of 64 %). Among all evaluated uterine structures, the junctional zone proved to be most sensitive to the influence of the acceleration factor. Statistical analysis showed statistically significant differences between image interpretation qualities between two radiologists of different experience levels (p < 0.05).

Conclusion: CS-SENSE accelerated T2 TSE sequence of the female pelvis shows image quality similar to that of conventional acquisitions with reduced acquisition time. CS-SENSE can moderately reduce scan time, providing many benefits without losing the image quality.

Keywords: Compressed SENSE accelerated imaging; Diagnostic quality assessment; Endometrial cancer; Magnetic resonance imaging.