Quantitative analysis of Fumonisin B1 using photoelectrochemical aptamer sensing strategy based on dual type II heterojunction K3PW12O40/CdS/CoSx

Man Wang; Kai Li; Guangbing Wan; Xiang Ren; Jinhui Feng; Jinxiu Zhao; Dan Wu; Dawei Fan; Qin Wei

doi:10.1016/j.talanta.2025.127587

Quantitative analysis of Fumonisin B1 using photoelectrochemical aptamer sensing strategy based on dual type II heterojunction K₃PW₁₂O₄₀/CdS/CoS_x

Talanta. 2025 Jan 12:287:127587. doi: 10.1016/j.talanta.2025.127587. Online ahead of print.

Authors

Man Wang¹, Kai Li², Guangbing Wan¹, Xiang Ren³, Jinhui Feng⁴, Jinxiu Zhao¹, Dan Wu¹, Dawei Fan¹, Qin Wei⁵

Affiliations

¹ Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, China.
² Shandong LiaoTai Environmental Technology Co., LTD, Liaocheng, 252004, Shandong, China.
³ Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, China. Electronic address: [email protected].
⁴ Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, China; Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, School of Chemistry and Chemical Engineering, Linyi University, Linyi, 276000, Shandong, China. Electronic address: [email protected].
⁵ Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan, 250022, China; Department of Chemistry, Sungkyunkwan University, Suwon, 16419, Republic of Korea. Electronic address: [email protected].

PMID: 39824058
DOI: 10.1016/j.talanta.2025.127587

Abstract

Fumonisin B1 (FB1) is a highly toxic fungal toxin that poses a serious threat to human health. Accordingly, realizing highly sensitive detection of FB1 is essential to safeguard people's health. In this study, a photoelectrochemical (PEC) aptamer sensor was successfully constructed with K₃PW₁₂O₄₀/CdS/CoS_x as the substrate material and with AgBiS₂ as the aptamer marker. Importantly, the utilization of AgBiS₂ as an aptamer marker can regulate the electron transfer pathway, resulting in a clear decrease in the photocurrent value. Due to the strong affinity between FB1 and its aptamer (t-DNA), it will cause the photoanode to release t-DNA-AgBiS₂, which can realize the effective recovery of photocurrent. Furthermore, the synthesized PEC aptamer sensor enables sensitive detection of FB1 and has a wider linear range of 100 fg/mL ∼1 μg/mL with a detection limit as low as 4.9 fg/mL. In short, this study provides a feasible PEC aptamer sensor strategy for sensitive detection of FB1, which paves a new way for the detection of other mycotoxins.

Keywords: AgBiS(2); Aptamer; Fumonisin B1; K(3)PW(12)O(40)/CdS/CoS(x); Photoelectrochemical.