A corrole-based derivative as an ultra-fast response and high selective fluorescent probe for Mg²⁺ and its application

A new corrole derivative bearing 8-hydroxyquinoline moiety, which was labeled as 8-HQ-Corrole, serves as an efficient fluorescent probe for Mg²⁺ in the presence of various interferents. This probe 8-HQ-Corrole displayed an ultra-fast response (2 s) to Mg²⁺ with an impressive detection limit (33 nM) and a significant fluorescence enhancement, accompanying with a blue shift from 667 to 653 nm in fluorescence spectrum. MS and Job's plot analysis indicated that the enhanced fluorescence response was attributable to the formation of 1:2 stoichiometric complex between to Mg²⁺ and 8-HQ-Corrole involving quinoline nitrogen and oxygen atoms. Furthermore, the capability of 8-HQ-Corrole for environmental and biological application has been demonstrated in water and living Hela cells.