Relationship between fundus of the eye examination and arterial stiffness

Front Cardiovasc Med. 2025 Jan 6:11:1516787. doi: 10.3389/fcvm.2024.1516787. eCollection 2024.

Abstract

This review addresses the correlation between arterial stiffness, measured by pulse wave velocity (PWV), and retinal microvascular changes, highlighting the retina as an important accessible window for inferences about cardiovascular health. Arterial stiffness, intrinsically linked to vascular aging and several comorbidities, results in damage to the microcirculation, including ocular vasculature, which can act as a predictor of cardiovascular and cerebrovascular outcomes. The review highlights the relationship between PWV assessment and funduscopic examination, with the aim of improving diagnostic accuracy and optimizing the clinical application of these tools in the management of cardiovascular and ophthalmological diseases, thus promoting more effective and early intervention.

Keywords: arterial stiffness; cardiovascular diseases; fundus of the eye; hypertension; pulse wave velocity.

Publication types

  • Review