The Co-IMPACT Consortium: Integrating Prostate-specific Membrane Antigen Positron Emission Tomography and Radiotherapy in Prostate Cancer Care

Vedang Murthy; Giulia Marvaso; Barbara A Jereczek-Fossa; Stephanie A Thoma; Marco Vogel; Nina-Sophie Schmidt-Hegemann; Mohamed Shelan; Shankar Siva; Tobias Hoelscher; Amar U Kishan; Jan C Peeken; Silke Gillessen; Matthias Guckenberger; Ken Herrmann; Wolfgang P Fendler; Thomas Zilli; Simon K B Spohn; Constantinos Zamboglou

doi:10.1016/j.eururo.2025.01.003

The Co-IMPACT Consortium: Integrating Prostate-specific Membrane Antigen Positron Emission Tomography and Radiotherapy in Prostate Cancer Care

Eur Urol. 2025 Jan 20:S0302-2838(25)00008-9. doi: 10.1016/j.eururo.2025.01.003. Online ahead of print.

Authors

Vedang Murthy¹, Giulia Marvaso², Barbara A Jereczek-Fossa², Stephanie A Thoma³, Marco Vogel⁴, Nina-Sophie Schmidt-Hegemann⁵, Mohamed Shelan⁶, Shankar Siva⁷, Tobias Hoelscher⁸, Amar U Kishan⁹, Jan C Peeken⁴, Silke Gillessen¹⁰, Matthias Guckenberger¹¹, Ken Herrmann¹², Wolfgang P Fendler¹², Thomas Zilli¹⁰, Simon K B Spohn¹³, Constantinos Zamboglou¹⁴

Affiliations

¹ Radiation Oncology Tata Memorial Centre Homi Bhabha National Institute Mumbai India.
² Division of Radiation Oncology, European Institute of Oncology, IRCCS Milan Italy; Department of Oncology and Hemato-oncology, University of Milan Milan Italy.
³ Department of Radiation Oncology, Kantonsspital Aarau Aarau Germany.
⁴ Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich Munich Germany; Institute of Radiation Medicine (IRM), Helmholtz Zentrum München (HMGU) GmbH, German Research Center for Environmental Health Neuherberg Germany.
⁵ Department of Radiation Oncology, University Hospital, LMU Munich Munich Germany.
⁶ Department of Radiation Oncology, Inselspital Bern University Hospital, University of Bern Bern Switzerland.
⁷ Department of Radiation Oncology, Peter MacCallum Cancer Centre Melbourne VIC Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne VIC Australia.
⁸ Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden Dresden Germany.
⁹ Department of Radiation Oncology, University of California-Los Angeles Los Angeles CA USA; Department of Urology, University of California-Los Angeles Los Angeles CA USA.
¹⁰ Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale Bellinzona Switzerland; Faculty of Biosciences, Università della Svizzera Italiana Lugano Switzerland.
¹¹ Department of Radiation Oncology, University Hospital Zurich University of Zurich Zurich Switzerland.
¹² Department of Nuclear Medicine, University of Duisburg-Essen Essen Germany; German Cancer Consortium, University Hospital Essen Essen Germany.
¹³ Department of Radiation Oncology, Medical Center - University of Freiburg Freiburg Germany; German Cancer Consortium (DKTK), Partner Site Freiburg Freiburg Germany.
¹⁴ Department of Radiation Oncology, Medical Center - University of Freiburg Freiburg Germany; German Oncology Center, European University Cyprus Limassol Cyprus. Electronic address: [email protected].

PMID: 39837736
DOI: 10.1016/j.eururo.2025.01.003

Abstract

The Co-IMPACT consortium addresses knowledge gaps in prostate-specific membrane antigen positron emission tomography-guided radiotherapy for prostate cancer by establishing a global database (46 centres from 16 countries) to standardise and analyse data across four distinguished clinical scenarios. A collaborative model with the Advanced Prostate Cancer Consensus Conference aligns urgent clinical needs with actionable research insights.

Publication types

Editorial