A stable and reusable aluminum-based metal-organic framework for the effective extraction of four aflatoxins from vegetable oils

The high specific surface area of metal-organic framework (MOF) materials endows them with efficient adsorption capabilities, thereby facilitating sample purification. In this study, a novel aluminum-based MOF (Al-MOF) was synthesized and employed as a solid-phase extraction (SPE) adsorbent for the purification of aflatoxins B₁ (AFB₁), AFB₂, AFG₁, and AFG₂ in vegetable oils. It was revealed that Al-MOF adsorbs aflatoxins through hydrogen bonding and π-π interactions. Under optimal SPE conditions, liquid chromatography-tandem mass spectrometry analysis yielded limits of detection ranging from 0.06 to 0.25 μg/kg and limits of quantification from 0.21 to 0.84 μg/kg for the four aflatoxins. Recovery rates at concentrations of 5, 10, and 20 μg/kg ranged from 74 % to 110 %, with coefficients of variation below 11 %. This method achieves efficient and cost-effective purification of aflatoxins in vegetable oils. Compared to national standard methods, this approach offers advantages such as lower material costs, ease of storage, and reusability.