Objective: The purpose of this study is to explore the application effect of early risk factor warning model of acute kidney injury combined with continuous renal replacement therapy in patients with severe acute pancreatitis, and to comprehensively evaluate the effects of this combined treatment model on patients'renal function recovery and complications through prospective studies.
Methods: This study adopted a rigorous random grouping method to ensure the balance and randomness of the grouping and minimize the interference of confounding factors on the research results. Specifically, with the help of a computer-generated random number sequence, patients who met the inclusion criteria were randomly assigned to the combined treatment group and the traditional treatment group.
Results: The incidence of acute kidney injury differed significantly between the two groups. The incidence of acute kidney injury in the traditional treatment group is as high as 35%, which is closely related to the natural course of the development of severe acute pancreatitis and the limitations of traditional treatment methods.
Conclusions: The application of early risk factor warning model of acute kidney injury combined with continuous renal replacement therapy in patients with severe acute pancreatitis has excellent performance in improving patient prognosis, guiding clinical decision-making, and optimizing the allocation of medical resources.