Short-duration dithranol therapy (SDDT) was compared to Dithrocream therapy in an open trial for the treatment of psoriasis. SDDT is based on the application of highly concentrated (1-2%) dithranol (anthralin) for a short period of time (10-20 min) and appeared to be clearly less staining and more comfortable than Dithrocream (0.1-0.5%). Both treatment methods appeared to be clinically effective; the SDDT method was slightly more effective than Dithrocream in this study.