Abstract
In 12 cases of CIDP under surveillance for 14 years, the main nerve biopsy findings were endoneural oedema and demyelination of nerve fibres. IgM deposition was found in 1 patient and IgG deposits in another. Electron microscopy revealed proliferation of the Schwann cells and mononuclear cell infiltration. The diagnostic criteria and nerve biopsy findings in CIDP are listed in the tables.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Autoimmune Diseases / immunology
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Autoimmune Diseases / pathology*
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Child
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Chronic Disease
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Demyelinating Diseases / drug therapy
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Demyelinating Diseases / immunology
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Demyelinating Diseases / pathology*
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Humans
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Immunoglobulin G / analysis
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Immunoglobulin M / analysis
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Immunosuppressive Agents / therapeutic use
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Microscopy, Electron
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Middle Aged
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Nerve Fibers, Myelinated / immunology
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Nerve Fibers, Myelinated / ultrastructure*
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Peripheral Nerves / immunology
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Peripheral Nerves / physiopathology*
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Peripheral Nerves / ultrastructure*
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Polyradiculoneuropathy / drug therapy
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Polyradiculoneuropathy / immunology
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Polyradiculoneuropathy / pathology*
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Schwann Cells / pathology
Substances
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Immunoglobulin G
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Immunoglobulin M
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Immunosuppressive Agents