The role of aryl hydrocarbon hydroxylase in skin tumor initiation by 7,12-dimethylbenz(a)anthracene and 1,2,5,6-dibenzanthracene using DNA binding and thymidine-3H incorporation into DNA as criteria

Cancer Res. 1974 Oct;34(10):2634-42.
No abstract available

MeSH terms

  • Administration, Topical
  • Animals
  • Benz(a)Anthracenes* / antagonists & inhibitors
  • Benz(a)Anthracenes* / metabolism
  • Carcinogens*
  • DNA / biosynthesis
  • DNA / metabolism
  • DNA, Neoplasm / biosynthesis
  • Female
  • Flavonoids / pharmacology
  • Mice
  • Mixed Function Oxygenases / antagonists & inhibitors
  • Mixed Function Oxygenases / biosynthesis*
  • Phenobarbital / pharmacology
  • Polycyclic Compounds
  • Proteins / metabolism
  • RNA / metabolism
  • Skin / metabolism
  • Skin Neoplasms / chemically induced*
  • Skin Neoplasms / enzymology
  • Thymidine / metabolism
  • Tritium

Substances

  • Benz(a)Anthracenes
  • Carcinogens
  • DNA, Neoplasm
  • Flavonoids
  • Polycyclic Compounds
  • Proteins
  • Tritium
  • RNA
  • DNA
  • Mixed Function Oxygenases
  • Thymidine
  • Phenobarbital