Abstract
Streptomycin-dependent Escherichia coli serotypes O 111, O 55 and O 26 were used to vaccinate young patas monkeys against these organisms by the oral route. Five administrations of 10(10) cells in 3-day intervals gave almost full protection to the animals against challenge with 9 to 11 minimal infective doses of homologous virulent organisms for at least 1 month, whether the three serotypes were administered singly or simultaneously.
MeSH terms
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Administration, Oral
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Animals
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Antibody Formation
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Antigens, Bacterial / analysis
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Bacterial Vaccines*
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Chromium Isotopes
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Densitometry
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Diarrhea / prevention & control
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Escherichia coli / immunology*
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Escherichia coli Infections / immunology*
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Escherichia coli Infections / prevention & control
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Feces / microbiology
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Genetics, Microbial
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Haplorhini
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Immunization
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Radioimmunoassay
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Serotyping
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Streptomycin
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Time Factors
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Vaccination
Substances
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Antigens, Bacterial
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Bacterial Vaccines
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Chromium Isotopes
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Streptomycin