Chronic haloperidol causes persistent increase in 3,4-dihydroxyphenylacetic acid (DOPAC) concentration in the substantia nigra but not in the ventral tegmental area

Brain Res. 1979 Oct 12;175(1):178-82. doi: 10.1016/0006-8993(79)90529-8.
No abstract available

Publication types

  • Comparative Study

MeSH terms

  • 3,4-Dihydroxyphenylacetic Acid / metabolism*
  • Animals
  • Caudate Nucleus / drug effects
  • Caudate Nucleus / metabolism
  • Cerebral Cortex / drug effects
  • Cerebral Cortex / metabolism
  • Haloperidol / pharmacology*
  • Kinetics
  • Male
  • Organ Specificity
  • Phenylacetates / metabolism*
  • Rats
  • Substantia Nigra / drug effects
  • Substantia Nigra / metabolism*
  • Tegmentum Mesencephali / drug effects
  • Tegmentum Mesencephali / metabolism*

Substances

  • Phenylacetates
  • 3,4-Dihydroxyphenylacetic Acid
  • Haloperidol