Modifications of pyrrolizidine alkaloid intoxication resulting from altered hepatic microsomal enzymes

Toxicol Appl Pharmacol. 1972 Nov;23(3):470-9. doi: 10.1016/0041-008x(72)90049-x.
No abstract available

MeSH terms

  • Animals
  • Chloramphenicol / administration & dosage
  • Chloramphenicol / pharmacology
  • Dose-Response Relationship, Drug
  • Drug Interactions
  • Injections, Subcutaneous
  • Lung / pathology
  • Male
  • Microsomes, Liver / drug effects
  • Microsomes, Liver / enzymology*
  • Myocardium / pathology
  • Pentobarbital / administration & dosage
  • Pentobarbital / pharmacology
  • Phenobarbital / administration & dosage
  • Phenobarbital / pharmacology
  • Poisoning / enzymology
  • Pyrrolizidine Alkaloids / administration & dosage
  • Pyrrolizidine Alkaloids / poisoning*
  • Pyrrolizidine Alkaloids / toxicity
  • Rats
  • Sleep / drug effects

Substances

  • Pyrrolizidine Alkaloids
  • Chloramphenicol
  • Pentobarbital
  • Phenobarbital