Role of testosterone binding to the androgen receptor in male sexual differentiation of patients with 5 alpha-reductase deficiency

J Steroid Biochem. 1979 Oct;11(4):1385-92. doi: 10.1016/0022-4731(79)90110-9.
No abstract available

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • 3-Oxo-5-alpha-Steroid 4-Dehydrogenase / deficiency*
  • 3-Oxo-5-alpha-Steroid 4-Dehydrogenase / metabolism
  • Adult
  • Binding, Competitive
  • Cells, Cultured
  • Child, Preschool
  • Dihydrotestosterone / metabolism
  • Disorders of Sex Development / metabolism
  • Female
  • Fibroblasts / metabolism
  • Humans
  • Kinetics
  • Male
  • Oxidoreductases / deficiency*
  • Receptors, Androgen / metabolism*
  • Receptors, Steroid / metabolism*
  • Sex Differentiation*
  • Sexual Maturation
  • Skin / metabolism
  • Testosterone / metabolism*

Substances

  • Receptors, Androgen
  • Receptors, Steroid
  • Dihydrotestosterone
  • Testosterone
  • Oxidoreductases
  • 3-Oxo-5-alpha-Steroid 4-Dehydrogenase