Non-Hodgkin's malignant lymphomata in adults: chemo-radiotherapy in stages III and IV

Br J Cancer Suppl. 1975 Mar:2:505-11.

Abstract

Patients presenting with Stage III or IV non-Hodgkin's malignant lymphoma were given chemotherapy; about 20% complete remission was obtained for both stages. The addition of radiotherapy increased the incidence to 70% in Stage III patients. The duration of first complete remission was longer for Stage III (25% of the patients are still in first remission at 7 years) than for Stage IV (0%). The survival was longer for nodular lymphosarcoma patients (25% are alive at 7 years for Stages III and IV) than for diffuse lymphosarcomata and reticulosarcomata (10%). Among the new drugs, VM 26 is able to produce a good frequency of remission in patients in relapse.

MeSH terms

  • Adult
  • Antineoplastic Agents / therapeutic use*
  • Azirines / therapeutic use
  • Bleomycin / therapeutic use
  • Cyclophosphamide / therapeutic use
  • Daunorubicin / therapeutic use
  • Etoposide / therapeutic use
  • Female
  • Humans
  • Lymphoma, Large B-Cell, Diffuse / drug therapy
  • Lymphoma, Large B-Cell, Diffuse / radiotherapy
  • Lymphoma, Large B-Cell, Diffuse / therapy*
  • Lymphoma, Non-Hodgkin / drug therapy
  • Lymphoma, Non-Hodgkin / radiotherapy
  • Lymphoma, Non-Hodgkin / therapy*
  • Male
  • Prednisone / therapeutic use
  • Procarbazine / therapeutic use
  • Teniposide / therapeutic use
  • Triethylenemelamine / therapeutic use
  • Vinblastine / therapeutic use
  • Vincristine / therapeutic use

Substances

  • Antineoplastic Agents
  • Azirines
  • Bleomycin
  • Procarbazine
  • Vincristine
  • Vinblastine
  • Etoposide
  • Cyclophosphamide
  • Teniposide
  • Triethylenemelamine
  • Prednisone
  • Daunorubicin