Local and Gastrointestinal reactions to intravenously administered cefoxitin and cefuroxime

Scand J Infect Dis. 1979;11(4):315-6. doi: 10.3109/inf.1979.11.issue-4.12.

Abstract

Side effects of cefoxitin and cefuroxime were noted in 2 different studies during intravenous treatment for at least 14 days. In the cefoxitin group of 33 patients thrombophlebitis was observed in 3 cases and diarrhoea in 4 cases. In the cefuroxime group of 31 patients 1 case of thrombophlebitis was noted and 5 cases of diarrhoea occurred. Most patients with diarrhoea had decreased renal function or received higher dosage of the antibodies than the other patients.

MeSH terms

  • Aged
  • Cefoxitin / administration & dosage
  • Cefoxitin / adverse effects*
  • Cefuroxime / administration & dosage
  • Cefuroxime / adverse effects*
  • Cephalosporins / adverse effects*
  • Diarrhea / chemically induced
  • Glomerular Filtration Rate
  • Half-Life
  • Humans
  • Injections, Intravenous
  • Thrombophlebitis / chemically induced

Substances

  • Cephalosporins
  • Cefoxitin
  • Cefuroxime