Study of dose-dependent metabolism of 5,5-diphenyl-hydantoin in the rat using new methodology for isolation and quantitation of metabolites in vivo and in vitro

MeSH terms

• Animals
• Bile / analysis
• Biotransformation
• Carbon Isotopes
• Chromatography, Gas
• Half-Life
• In Vitro Techniques
• Male
• Mass Spectrometry
• Microsomes, Liver / metabolism*
• Perfusion
• Phenytoin / administration & dosage
• Phenytoin / blood
• Phenytoin / metabolism*
• Rats
• Silicon