Structure of a family of rat amylase genes

Nature. 1980 Sep 11;287(5778):117-22. doi: 10.1038/287117a0.

Abstract

The sequences of two cloned rat pancreatic amylase cDNAs comprising 95% of the mRNA sequence are reported. Analysis of cloned rat genomic DNA fragments using cloned cDNA probes indicates that the rat genome contains multiple closely related amylase genes in which the cDNA sequences are distributed within a region 9 kilobases in length and are interrupted by at least seven intervening sequences.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Amylases / genetics*
  • Animals
  • Base Sequence
  • Genes
  • Genetic Linkage
  • Pancreas / enzymology*
  • RNA, Messenger / genetics*
  • Rats
  • Structure-Activity Relationship
  • alpha-Amylases / genetics*

Substances

  • RNA, Messenger
  • Amylases
  • alpha-Amylases

Associated data

  • GENBANK/J00703