Immunological cross-reactivity between H-2Dk product and DTIC-treated H-2d lymphoma

J Immunogenet. 1982 Dec;9(6):407-12. doi: 10.1111/j.1744-313x.1982.tb01002.x.

Abstract

The experiments reported here concern the characterization by techniques of in vitro cell-mediated immunity of the antigens induced by 5-(3,3' dimethyl-1-triazine)-imidazole-4-carboxamide (DTIC) on L1210, a chemically-induced lymphoma of DBA/2 mice (H-2d). This series of experiments with the DTIC-treated L1210 tumour show the presence of an 'H-2D'-like antigen which resembles the Dk gene product/s of the H-2k haplotype.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cross Reactions
  • Dacarbazine / therapeutic use*
  • Epitopes
  • H-2 Antigens / immunology*
  • Immunity, Cellular
  • In Vitro Techniques
  • Leukemia L1210 / drug therapy
  • Leukemia L1210 / immunology
  • Lymphoma / drug therapy
  • Lymphoma / immunology*
  • Mice
  • Mice, Inbred Strains

Substances

  • Epitopes
  • H-2 Antigens
  • Dacarbazine