Hemoglobin enhancement of experimental infection of mice with Pasteurella haemolytica

Am J Vet Res. 1983 Aug;44(8):1545-6.

Abstract

A 2% hemoglobin preparation injected into mice along with Pasteurella haemolytica culture was found to be as good an enhancer of virulence as a 7% swine gastric mucin preparation. The hemoglobin preparation was easier to prepare and was less toxic than mucin for mice when injected intraperitoneally.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Cattle / microbiology
  • Chickens / microbiology
  • Disease Models, Animal*
  • Gastric Mucins* / pharmacology
  • Hemoglobins*
  • Iron / pharmacology
  • Lung / microbiology
  • Male
  • Mice
  • Mice, Inbred Strains / microbiology*
  • Pasteurella / pathogenicity*
  • Pasteurella Infections / microbiology
  • Pasteurella Infections / veterinary*
  • Rodent Diseases / microbiology*
  • Sheep / microbiology
  • Swine
  • Virulence / drug effects

Substances

  • Gastric Mucins
  • Hemoglobins
  • Iron