Evaluation of toxicity of intravitreal antineoplastic drugs

Ophthalmic Surg. 1984 May;15(5):411-3.

Abstract

We evaluated the toxic and nontoxic doses of eight antineoplastic drugs in the vitreous cavity of rabbits. These drugs may have implications in the prevention of cell proliferation in the vitreous.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antineoplastic Agents / toxicity*
  • Bleomycin / toxicity
  • Cisplatin / toxicity
  • Cytarabine / toxicity
  • Dactinomycin / toxicity
  • Doxorubicin / toxicity
  • Etoposide / toxicity
  • Injections
  • Mitomycins / toxicity
  • Rabbits
  • Retina / pathology
  • Vincristine / toxicity
  • Vitreous Body*

Substances

  • Antineoplastic Agents
  • Mitomycins
  • Cytarabine
  • Bleomycin
  • Dactinomycin
  • Vincristine
  • Etoposide
  • Doxorubicin
  • Cisplatin