Mu dX, a derivative of Mu d1 (lac Apr) which makes stable lacZ fusions at high temperature

J Bacteriol. 1983 Nov;156(2):970-4. doi: 10.1128/jb.156.2.970-974.1983.

Abstract

We describe defective Mu phage Mu dX (Mu d1 Bx::Tn9 [lac Apr Cmr]) which is useful for insertion mutagenesis and for construction of lac operon fusions in vivo. Mu dX retains the insertion properties of Mu d1 but produces temperature-resistant lysogens and transposes at a reduced frequency. A method is described to convert existing Mu d1 insertions to Mu dX.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacteriophage mu / genetics*
  • Escherichia coli / genetics*
  • Genotype
  • Lac Operon*
  • Lysogeny
  • Mutation*
  • Species Specificity
  • Temperature
  • Transduction, Genetic