In 4 patients with Hodgkin's disease treated with chemotherapy persistent residual masses, remarkable by their initial volume in 3 cases, were surgically removed. Histological examination showed that the masses were histologically stable and non-evolutive. The incidence of residual masses is discussed with a review of the literature. These masses, which should not be confused with therapeutic failures, constitute a striking example of the special place occupied by surgery in certain forms of Hodgkin's disease.