Abstract
In 19 postmenopausal women, basal serum levels of cortisol, unconjugated dehydroepiandrosterone (DHA), dehydroepiandrosterone sulphate (DHAS), testosterone and unconjugated and total estrone were measured both before and during an ACTH test. A positive correlation was found both between basal levels of DHAS and the DHA response to ACTH, respectively, and trabecular bone mineral content of the distal forearm. A significant correlation was also observed between bone mineral content and precancerous/cancerous states of the uterine epithelium.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adrenal Cortex Hormones / blood*
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Adrenocorticotropic Hormone / pharmacology
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Bone and Bones / analysis*
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Dehydroepiandrosterone / analogs & derivatives
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Dehydroepiandrosterone / blood
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Dehydroepiandrosterone Sulfate
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Endometrium / pathology*
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Estrone / blood
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Female
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Forearm / analysis
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Humans
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Hydrocortisone / blood
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Menopause*
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Middle Aged
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Minerals / analysis*
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Osteoporosis / etiology
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Testosterone / blood
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Uterine Neoplasms / etiology
Substances
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Adrenal Cortex Hormones
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Minerals
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Estrone
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Testosterone
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Dehydroepiandrosterone
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Dehydroepiandrosterone Sulfate
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Adrenocorticotropic Hormone
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Hydrocortisone