[Virilizing luteoma of pregnancy. Relation to polycystic ovaries]

Sem Hop. 1983 Dec 1;59(44):3053-7.
[Article in French]

Abstract

Luteoma of pregnancy is a benign uncommon ovarian tumor which develops during pregnancy and disappears completely after delivery. It can virilize the mother and female foetus. The coexistence of this ovarian tumor with polycystic ovarian disease is well known but no causal relation has been demonstrated. In polycystic ovarian disease, luteinization is the result of persistent stimulation of the ovary by elevated levels of LH, whereas HCG has been suggested as a factor in the pathogenesis of luteoma. Though not a requisite factor, ovarian polycystic disease promotes the development of luteoma. However, the role of other hormonal and biochemical factors is still unknown.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Androgens / metabolism
  • Chorionic Gonadotropin / pharmacology
  • Female
  • Humans
  • Luteinizing Hormone / pharmacology
  • Ovarian Neoplasms / etiology
  • Ovarian Neoplasms / metabolism*
  • Polycystic Ovary Syndrome / complications*
  • Pregnancy
  • Pregnancy Complications, Neoplastic / etiology*
  • Thecoma / etiology
  • Thecoma / metabolism*
  • Virilism / etiology*

Substances

  • Androgens
  • Chorionic Gonadotropin
  • Luteinizing Hormone