The original experimental results and review of the literary data on the composition of total extractable Lipids in Streptomyces genus strains at the different growth stages grown on various composition media are given. The results of the investigation on lipids (including those of the membranes) which have not been earlier found in Streptomycetes are discussed. Special attention is given to changes of the membrane lipid component in connection with the growth phases and cultural conditions, particularly to the different rate of the membrane nitrogen-containing lipids interchange depending on the phosphate content in the medium.