Abstract
Two cases of adult histiocytosis X have been studied using monoclonal antibodies on skin sections by two techniques: indirect immunofluorescence and immunoperoxidase. This study confirm: --that histiocytosis X express two specific antigens Ia and T6, --the relations between Langerhans cell and histiocytosis X. Especially, it suggests that histiocytosis X cell would be a dedifferentiated cell with receptors OKT4 and OKT10.
Publication types
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Case Reports
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Comparative Study
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Antibodies, Monoclonal / immunology*
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Female
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Fluorescent Antibody Technique
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Histiocytosis, Langerhans-Cell / immunology*
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Histiocytosis, Langerhans-Cell / pathology
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Histocompatibility Antigens Class II / analysis
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Humans
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Immunoenzyme Techniques
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Langerhans Cells / immunology
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Skin / pathology
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Skin / ultrastructure
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Skin Diseases / immunology*
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Skin Diseases / pathology
Substances
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Antibodies, Monoclonal
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Histocompatibility Antigens Class II