Abstract
After recalling the main studies about the fragile sites, a fra (2) (q11) in a girl with familial lymphohistiocytosis is described. The influence of medicine, inducers, mutagenic agents are analysed.
Publication types
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Case Reports
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English Abstract
MeSH terms
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4-Nitroquinoline-1-oxide / pharmacology
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Adult
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Bromodeoxyuridine / pharmacology
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Cells, Cultured
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Chromosome Fragile Sites
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Chromosome Fragility*
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Chromosomes, Human, 1-3*
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Distamycins / pharmacology
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Female
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Humans
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Infant
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Interferon Type I / pharmacology
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Karyotyping
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Lymphatic Diseases / complications
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Lymphatic Diseases / genetics*
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Lymphocytes / drug effects
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Lymphocytosis / complications
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Lymphocytosis / genetics*
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Male
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Methyl Methanesulfonate / pharmacology
Substances
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Distamycins
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Interferon Type I
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4-Nitroquinoline-1-oxide
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stallimycin
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Methyl Methanesulfonate
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Bromodeoxyuridine