Abstract
A comparison of the serological responses to a reovirus administered by the eye-drop, intramuscular, oral and subcutaneous routes was made in three-week-old chickens. Their patterns of virus shedding were also compared. All four routes resulted in an antibody response and no virus excretion in faeces more than two to three weeks after administration. The oral route represented the most favourable route for live reovirus vaccine administration.
MeSH terms
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Administration, Oral
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Animals
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Antibodies, Viral / biosynthesis
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Chickens / immunology*
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Chickens / microbiology
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Feces / microbiology
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Immunodiffusion / veterinary
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Injections, Intramuscular / veterinary
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Injections, Subcutaneous / veterinary
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Neutralization Tests
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Ophthalmic Solutions
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Reoviridae / immunology*
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Reoviridae / isolation & purification
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Vaccines, Attenuated / administration & dosage
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Viral Vaccines / administration & dosage*
Substances
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Antibodies, Viral
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Ophthalmic Solutions
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Vaccines, Attenuated
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Viral Vaccines