Use of gene cloning to determine polarity of an operon: genes carAB of Escherichia coli

J Bacteriol. 1980 Aug;143(2):921-5. doi: 10.1128/jb.143.2.921-925.1980.

Abstract

A gene-cloning approach was used to determine the transcription polarity of the carbamoylphosphate operon (carAB) of Escherichia coli. In agreement with the accompanying paper (J. Bacteriol. 143:914-920, 1980), our results lead to the conclusion that carA is the proximal gene of the carAB operon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteriophage lambda / genetics
  • Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) / genetics*
  • Cloning, Molecular / methods
  • Escherichia coli / genetics*
  • Gene Expression Regulation
  • Genes, Regulator
  • Ligases / genetics*
  • Operon*
  • Plasmids
  • Transcription, Genetic

Substances

  • Ligases
  • Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)