Abstract
The frequency and intensity of discomfort and pain at the site of injection during intravenous infusion of theophylline sodium glycinate and theophylline ethylenediamine were compared in a single blind crossover study on 6 healthy adult volunteers. The preparation containing theophylline sodium glycinate was significantly better tolerated than theophylline ethylenediamine.
Publication types
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Clinical Trial
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Comparative Study
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Controlled Clinical Trial
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English Abstract
MeSH terms
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Adult
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Drug Combinations
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Ethylenediamines / administration & dosage
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Ethylenediamines / adverse effects*
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Female
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Humans
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Infusions, Parenteral*
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Male
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Middle Aged
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Pain / chemically induced
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Solutions / adverse effects
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Theophylline / administration & dosage*
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Theophylline / adverse effects
Substances
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Drug Combinations
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Ethylenediamines
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Solutions
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Theophylline