Kinetic study of the hydrolysis of 1-(4-nitrophenyl)-3-methyltriazene in aqueous solution and in the presence of surfactants

J Pharm Sci. 1984 Dec;73(12):1691-4. doi: 10.1002/jps.2600731206.

Abstract

The hydrolysis of 1-(4-nitrophenyl)-3-methyltriazene in aqueous solution has been studied over a pH range of 3-14. The effect of the anionic and cationic surfactants (sodium lauryl sulfate and hexadecyltrimethylammonium bromide) on the rate of hydrolysis was investigated. The quaternary ammonium bromide causes a rate decrease at all pH values studied, while sodium lauryl sulfate enhances the acid-catalyzed hydrolysis and decreases the observed rate constants in the pH-independent region. The results are discussed in terms of the current theory of micellar effects.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cetrimonium
  • Cetrimonium Compounds
  • Chemical Phenomena
  • Chemistry, Physical
  • Hydrolysis
  • Kinetics
  • Micelles
  • Sodium Dodecyl Sulfate
  • Surface-Active Agents*
  • Triazenes*

Substances

  • Cetrimonium Compounds
  • Micelles
  • Surface-Active Agents
  • Triazenes
  • Sodium Dodecyl Sulfate
  • 1-(4-nitrophenyl)-3-methyltriazene
  • Cetrimonium