Action of the antibiotics of the iturin group on artificial membranes

J Antibiot (Tokyo). 1984 Jun;37(6):646-51. doi: 10.7164/antibiotics.37.646.

Abstract

The action of iturin A and bacillomycin L on vesicles of dipalmitoylphosphatidylcholine (DPPC) and DPPC-cholesterol was studied. Iturin A destroyed the vesicles, bacillomycin L bound with DPPC vesicles and destroyed vesicles containing DPPC and cholesterol. These results are discussed in comparison with the action of antibiotics of the iturin group on cytoplasmic membranes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents*
  • Antifungal Agents*
  • Carbon Radioisotopes
  • Chemical Phenomena
  • Chemistry
  • Cholesterol*
  • Kinetics
  • Liposomes*
  • Peptides*
  • Peptides, Cyclic
  • Pulmonary Surfactants*
  • Tritium

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Carbon Radioisotopes
  • Liposomes
  • Peptides
  • Peptides, Cyclic
  • Pulmonary Surfactants
  • Tritium
  • iturin A
  • bacillomycin L
  • Cholesterol