Abstract
Experimental amyotrophic leukospongiosis (ALSP) has first been reproduced in 2 squirrel monkeys 16 and 23 months after inoculation of the animals with a brain suspension from the patient who had died of this disease. From the brain cell cultures of the monkeys a hemadsorbing agent was isolated which induced cell proliferation and was inhibited by the antisera from patients with ALSP.
MeSH terms
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Animals
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Brain Diseases / microbiology*
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Brain Diseases / pathology
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Cells, Cultured
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Central Nervous System / microbiology
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Central Nervous System / pathology
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Disease Models, Animal
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Motor Neurons / pathology
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Muscle Hypotonia / microbiology
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Muscle Hypotonia / pathology
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Muscular Atrophy / microbiology
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Muscular Atrophy / pathology*
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Paralysis / microbiology
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Paralysis / pathology*
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Saimiri
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Slow Virus Diseases / microbiology
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Slow Virus Diseases / pathology*
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Time Factors