IgA nephropathy: clinicopathology and immunopathology

Contrib Nephrol. 1978:9:88-100. doi: 10.1159/000401436.

Abstract

In a total of 283 biopsies, 100 (35%) were found to be IgA nephropathy. The incidence reached 40% among primary glomerulonephropathies. On the basis of histopathologic changes in glomeruli, these biopsies were classified into 3 groups. The criteria employed correlated well with clinical, laboratory and immunofluorescent findings. Immune complex pathogenesis was discussed in relation to our findings.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Complement System Proteins / analysis
  • Female
  • Glomerulonephritis / immunology
  • Glomerulonephritis / pathology*
  • Glycoproteins / analysis
  • Humans
  • Immunoglobulin A / analysis*
  • Immunoglobulin G / analysis
  • Immunoglobulin M / analysis
  • Kidney Glomerulus / immunology
  • Kidney Glomerulus / pathology*
  • Kidney Glomerulus / ultrastructure
  • Male
  • Middle Aged
  • Properdin / analysis

Substances

  • Glycoproteins
  • Immunoglobulin A
  • Immunoglobulin G
  • Immunoglobulin M
  • Properdin
  • Complement System Proteins