Alloxan therapy for nesidioblastosis

J Pediatr Surg. 1984 Feb;19(1):87-9. doi: 10.1016/s0022-3468(84)80024-x.

Abstract

Two patients with nesidioblastosis presented to the Royal Hospital for Sick Children in Glasgow and developed recurrent hypoglycemia after subtotal pancreatectomy. They were treated successfully with alloxan (mesoxalyl urea). Alloxan is recommended as an alternative to further radical surgery.

Publication types

  • Case Reports

MeSH terms

  • Alloxan / therapeutic use*
  • Blood Glucose / analysis
  • Humans
  • Hyperinsulinism / therapy
  • Hypoglycemia / drug therapy
  • Infant
  • Infant, Newborn
  • Infant, Premature, Diseases / drug therapy
  • Pancreatectomy
  • Pancreatic Diseases / drug therapy*
  • Postoperative Complications / drug therapy
  • Recurrence

Substances

  • Blood Glucose
  • Alloxan