Planned third-party transfusions prior to first transplantations from liver related donors

Scand J Urol Nephrol Suppl. 1981:64:152-6.

Abstract

Seventy-nine first living related donor transplants performed in Gothenburg, Sweden, from April 1977 to October 1980 were studied. The patient survival was 97% at 30 months. The graft survival in HLA-identical sibling combination was 100%. Thirty previously non-transfused recipients of one-haplotype mismatched grafts were given 2 units of third-party blood as preparation for transplantation. The graft survival was 92% at 30 months. No patients became sensitized against their donor. Thirty-one recipients of haplotype-mismatched grafts, previously transfused for medical reasons, had a graft survival of 82% at 30 months. The deliberate third-party blood transfusion protocol has been rewarding and resulted in a highly satisfactory graft survival.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antilymphocyte Serum / immunology
  • Blood Transfusion*
  • Family Health*
  • Family*
  • Glomerular Filtration Rate
  • Graft Survival
  • HLA Antigens / genetics
  • Humans
  • Kidney / physiology
  • Kidney Failure, Chronic / mortality
  • Kidney Failure, Chronic / therapy
  • Kidney Transplantation*
  • Preoperative Care
  • Tissue Donors*

Substances

  • Antilymphocyte Serum
  • HLA Antigens