Abstract
Bath immunization of carp (Cyprinus carpio L) resulted in protection of fish at natural challenge. Stimulation of leukocytes derived from thymus, spleen, anterior kidney and mid-kidney of fish immunized with Flexibacter columnaris bacterin revealed the presence of antigen sensitized cells in all lymphoid tissues except the anterior kidney. After 28 days a response was obtained in thymus and spleen leukocyte cultures.
MeSH terms
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Animals
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Antigens, Bacterial / immunology
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Bacterial Infections / immunology
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Bacterial Infections / veterinary
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Bacterial Vaccines / administration & dosage
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Carps
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Female
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Fish Diseases / immunology*
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Immunization / methods
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Immunization / veterinary*
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Kidney / cytology
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Leukocytes / immunology*
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Lymphocyte Activation
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Male
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Mitogens / pharmacology
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Myxococcales / immunology*
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Spleen / cytology
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Thymus Gland / cytology
Substances
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Antigens, Bacterial
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Bacterial Vaccines
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Mitogens