Optimal insulin delivery in diabetic ketoacidosis (DKA) and hyperglycemic, hyperosmolar nonketotic coma (HHNC)

Diabetes Care. 1982 May-Jun:5 Suppl 1:78-87.

Abstract

Both diabetic ketoacidosis (DKA) and hyperglycemic, hyperosmolar nonketotic coma (HHNC) are stressful metabolic occurrences brought about by the orchestration of numerous events. Adequate hydration and replacement of electrolytes, along with physiologic doses of insulin, are treatment objectives for both of these conditions. Additionally, the physician must search for the factors precipitating these events and frequently evaluate the patient's overall condition.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Biological Availability
  • Blood Glucose / analysis
  • Diabetes Mellitus / drug therapy
  • Diabetes Mellitus, Type 2 / metabolism
  • Diabetic Coma / drug therapy*
  • Diabetic Ketoacidosis / drug therapy*
  • Humans
  • Hyperglycemic Hyperosmolar Nonketotic Coma / drug therapy*
  • Insulin / administration & dosage*
  • Insulin / metabolism
  • Insulin Infusion Systems
  • Obesity

Substances

  • Blood Glucose
  • Insulin