Postzygotic D/D translocation homozygosity associated with recurrent abortions

Am J Med Genet. 1983 Jul;15(3):389-92. doi: 10.1002/ajmg.1320150304.

Abstract

A Robertsonian translocation involving homologous D chromosomes was found in two cases with a history of recurrent abortions. In the first case the propositus was a 37-year-old phenotypically normal man who had a balanced t(14q14q) translocation. In the second case, a 27-year-old phenotypically normal woman was found to be a balanced t(15q15q) translocation carrier. The recurrent abortions in both cases were probably owing to this translocation.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Habitual / genetics*
  • Adult
  • Chromosome Aberrations / complications*
  • Chromosome Disorders
  • Chromosomes, Human, 13-15*
  • Female
  • Homozygote
  • Humans
  • Male
  • Pregnancy
  • Translocation, Genetic*