Abstract
We tested the efficacy of scopolamine delivered by transdermal patch in preventing emesis induced by cisplatin as a single agent or in combination. The administration of scopolamine by transdermal patch resulted in acceptable side effects but was ineffective in controlling cisplatin-induced emesis.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Adult
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Cisplatin / adverse effects*
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Drug Evaluation
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Female
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Humans
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Male
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Middle Aged
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Neoplasms / drug therapy
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Placebos
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Scopolamine / administration & dosage
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Scopolamine / therapeutic use*
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Vomiting / chemically induced
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Vomiting / prevention & control*
Substances
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Placebos
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Scopolamine
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Cisplatin