Two groups of college women were administered the Hand Test and selected scales from the Guilford-Zimmerman Temperament Survey. One group was tested in the premenstrual phase of the menstrual cycle (days 20-25); the other group at the beginning of the cycle (days 5-9). Significant differences were obtained, but the results did not corroborate earlier findings that negative personality characteristics are associated with the premenstrual phase of the cycle. The implications of the results and relevant methodological considerations are discussed.