Inhibition of deoxyribonucleic acid polymerases of human leukemic leukocytes by 2',3'-dideoxythymidine triphosphate

Biochem Pharmacol. 1980 Apr 15;29(8):1149-53. doi: 10.1016/0006-2952(80)90410-4.
No abstract available

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • DNA-Directed DNA Polymerase / blood
  • Dideoxynucleotides
  • Humans
  • In Vitro Techniques
  • Kinetics
  • Leukemia, Myeloid, Acute / enzymology*
  • Magnesium / pharmacology
  • Manganese / pharmacology
  • Nucleic Acid Synthesis Inhibitors*
  • Polydeoxyribonucleotides
  • Substrate Specificity
  • Thymine Nucleotides / pharmacology*

Substances

  • Dideoxynucleotides
  • Nucleic Acid Synthesis Inhibitors
  • Polydeoxyribonucleotides
  • Thymine Nucleotides
  • Manganese
  • DNA-Directed DNA Polymerase
  • Magnesium
  • 2',3'-dideoxythymidine triphosphate