Abstract
New 2,3-dihydrofuran-2,3-dione derivatives (1-11) were obtained by condensation of oxalyl chloride with Schiff bases of acetyl- or benzoylacetone and aromatic amines. These compounds showed only weak sedative action and weak analgesic effect.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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5-Hydroxytryptophan / pharmacology
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Analgesics / chemical synthesis
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Animals
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Anticonvulsants
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Chemical Phenomena
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Chemistry
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Furans / chemical synthesis*
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Furans / pharmacology
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Hexobarbital / pharmacology
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Lethal Dose 50
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Male
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Mice
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Motor Activity / drug effects
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Sleep / drug effects
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Time Factors
Substances
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Analgesics
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Anticonvulsants
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Furans
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Hexobarbital
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5-Hydroxytryptophan