Bendectin and fetal development. A study of Boston City Hospital

Am J Obstet Gynecol. 1982 Jan 15;142(2):209-13. doi: 10.1016/s0002-9378(16)32338-9.

Abstract

As part of a prospective study investigating maternal characteristics and habits during pregnancy and their impact on fetal development, 1,690 mother/infant pairs were studied. Of the mothers, 375 reported using Bendectin during pregnancy. Multivariate analyses examining birth weight, length, head circumference, gestational age, and congenital malformations as dependent variables demonstrated no associations between Bendectin exposure and adverse fetal outcome.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Abnormalities, Drug-Induced*
  • Antiemetics / adverse effects*
  • Cyclohexanecarboxylic Acids / adverse effects*
  • Dicyclomine / adverse effects*
  • Doxylamine / adverse effects*
  • Drug Combinations / adverse effects
  • Female
  • Humans
  • Infant, Newborn
  • Interviews as Topic
  • Pregnancy
  • Prenatal Care
  • Prospective Studies
  • Pyridines / adverse effects*
  • Pyridoxine / adverse effects*
  • Risk
  • Teratogens

Substances

  • Antiemetics
  • Cyclohexanecarboxylic Acids
  • Drug Combinations
  • Pyridines
  • Teratogens
  • dicyclomine, doxylamine, pyridoxine drug combination
  • Dicyclomine
  • Doxylamine
  • Pyridoxine