Differential voltammetric measurement of catecholamines and ascorbic acid at surface-modified carbon filament microelectrodes

Brain Res. 1982 Mar 4;235(1):179-84. doi: 10.1016/0006-8993(82)90210-4.

Abstract

Triple-barrel carbon filament microelectrodes were chemically and electrochemically oxidized to allow resolution of ascorbic acid from catecholamines during differential pulse voltammetric scans. The contribution of current from DOPAC to the catecholamine signal was minimized by this treatment. These electrodes exhibit linearity over a wide range of concentrations and long-term response stability.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • 3,4-Dihydroxyphenylacetic Acid / metabolism
  • Animals
  • Ascorbic Acid / metabolism*
  • Catecholamines / metabolism*
  • Cats
  • Central Nervous System / metabolism*
  • Dopamine / metabolism
  • Electrochemistry / methods
  • Locus Coeruleus / metabolism
  • Microelectrodes

Substances

  • Catecholamines
  • 3,4-Dihydroxyphenylacetic Acid
  • Ascorbic Acid
  • Dopamine