Because opinions on the advisability of splenectomy, especially in children, have recently changed considerably, an experiment was set up to study the application of 3 hemostatics in deep injuries to the liver and to the spleen in 29 rabbits and to dogs. Of the 3 substances tested GRF-adhesive and Avitene appeared to give reasonably good results in splenic injuries, but a supplementary suturing procedure or a ligation of the vessels seemed desirable. The effect of GRF-adhesive on liver injuries was satisfactory.